National Registry for Juvenile-Onset Recurrent Respiratory Papillomatosis

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National registry for juvenile-onset recurrent respiratory papillomatosis.

BACKGROUND Juvenile-onset recurrent respiratory papillomatosis (JORRP) is an infrequent but debilitating disease. Because JORRP is uncommon, it has proven difficult for studies at single institutions to accurately evaluate its natural history. OBJECTIVE To characterize the clinical spectrum of JORRP. DESIGN Standardized retrospective and prospective medical record abstraction. SETTING Twe...

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Recurrent Respiratory Papillomatosis (RRP)—Juvenile Onset

In this article, we describe the treatment of long standing juvenile-onset recurrent respiratory papillomatosis (JORRP) with eventual transformation to carcinoma in a patient who lived to the age of 73. Treatment modalities consisted of bronchoscopy and local excision initially. Later, YAG and CO2 laser debulking were used. Radiotherapy, chemotherapy with carboplatin (300 mg/m2) and 5-FU (600 m...

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Predictors of remission in juvenile-onset recurrent respiratory papillomatosis.

OBJECTIVE To determine factors associated with remission of juvenile-onset recurrent respiratory papillomatosis (JORRP). DESIGN Longitudinal study. SETTING Twenty-two tertiary care centers located across the United States. STUDY PARTICIPANTS AND METHODS The study included 165 patients diagnosed as having JORRP between January 1, 1997, and December 31, 2000. Kaplan-Meier curves and Cox pro...

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The cost of juvenile-onset recurrent respiratory papillomatosis.

OBJECTIVE To assess the medical costs and the number of quality-adjusted life years lost owing to juvenile-onset recurrent respiratory papillomatosis (JORRP). DESIGN We examined hospital and physician charges for JORRP surgical procedures in Maryland in 1994 adjusting for inflation and the cost-charge ratio. Centers for Disease Control and Prevention data on treatment intensity for JORRP were...

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Prevalence of dysplasia in juvenile-onset recurrent respiratory papillomatosis.

OBJECTIVES To quantify the prevalence of dysplasia and to evaluate the impact of use of cidofovir in recurrent respiratory papilloma biopsy specimens obtained from a pediatric population. DESIGN Retrospective review of patient medical records and histopathologic test results from January 1, 1998, through December 31, 2008. SETTING Children's Hospital of Wisconsin. PATIENTS Patients with a...

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ژورنال

عنوان ژورنال: Archives of Otolaryngology–Head & Neck Surgery

سال: 2003

ISSN: 0886-4470

DOI: 10.1001/archotol.129.9.976